Yasuyuki Sasaguri Selected Research

Inflammation (Inflammations)

12/2018	Relationship between CCL22 Expression by Vascular Smooth Muscle Cells and Macrophage Histamine Receptors in Atherosclerosis.
1/2014	Marine hydroquinone zonarol prevents inflammation and apoptosis in dextran sulfate sodium-induced mice ulcerative colitis.
12/2013	Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model.
9/2013	Histamine receptors expressed in circulating progenitor cells have reciprocal actions in ligation-induced arteriosclerosis.
4/2011	Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level.
3/2011	Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T cells and D1-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model.
8/2010	Histamine regulation in glucose and lipid metabolism via histamine receptors: model for nonalcoholic steatohepatitis in mice.
3/2010	[Role of histamine in atherosclerotic lesions].
6/2005	Local expression of platelet-activating factor-acetylhydrolase reduces accumulation of oxidized lipoproteins and inhibits inflammation, shear stress-induced thrombosis, and neointima formation in balloon-injured carotid arteries in nonhyperlipidemic rabbits.
2/2005	Involvement of estrogen in the pathogenesis of cyclophosphamide-induced cystitis in rats.

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Yasuyuki Sasaguri Research Topics

Disease

21	Atherosclerosis 12/2018 - 01/2004
20	Neoplasms (Cancer) 01/2019 - 01/2003
11	Inflammation (Inflammations) 12/2018 - 01/2005
6	Hyperlipidemias (Hyperlipidemia) 02/2015 - 08/2010
5	Atherosclerotic Plaque (Atheroma) 12/2016 - 05/2005
4	Carcinoma (Carcinomatosis) 01/2018 - 01/2003
4	Non-alcoholic Fatty Liver Disease 07/2016 - 08/2010
4	Fibrosis (Cirrhosis) 03/2014 - 09/2002
4	Vascular System Injuries 02/2013 - 05/2005
4	Neointima 05/2008 - 05/2005
3	Necrosis 01/2019 - 08/2012
3	Neoplasm Metastasis (Metastasis) 01/2016 - 05/2011
3	Adenocarcinoma 02/2015 - 05/2003
3	Arteriosclerosis 09/2013 - 02/2005
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2016 - 12/2013
2	Squamous Cell Carcinoma of Head and Neck 01/2016 - 12/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 05/2015 - 06/2009
2	Myocardial Infarction 05/2015 - 04/2008
2	Thrombocytopenia (Thrombopenia) 05/2015 - 10/2012
2	Insulin Resistance 12/2013 - 08/2010
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2012 - 11/2010
2	Rheumatoid Arthritis 03/2011 - 10/2004
2	Hypoxia (Hypoxemia) 03/2011 - 10/2008
2	Aneurysm (Aneurysms) 12/2008 - 04/2006
2	Colonic Neoplasms (Colon Cancer) 09/2006 - 05/2004
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2006 - 01/2005
2	Small Cell Carcinoma 01/2003 - 02/2002
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2003 - 02/2002
1	Skin Ulcer 01/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Adenocarcinoma of Lung 08/2016
1	Disease Progression 01/2016
1	Chest Pain (Chest Pains) 05/2015
1	Thrombotic Thrombocytopenic Purpura 05/2015
1	Cardiac Arrhythmias (Arrythmia) 05/2015
1	Ischemia 05/2015
1	Sudden Death 05/2015
1	Myxoma (Myxomas) 06/2014
1	Ulcerative Colitis 01/2014
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2014
1	Ulcer 01/2014

Drug/Important Bio-Agent (IBA)

17	Histamine (Histamine Dihydrochloride)FDA Link 12/2018 - 01/2004
10	CholesterolIBA 07/2016 - 05/2005
9	Histamine Receptors (Histamine Receptor)IBA 12/2018 - 02/2005
7	ApolipoproteinsIBA 02/2015 - 05/2005
6	EnzymesIBA 05/2015 - 06/2004
6	Proteins (Proteins, Gene)FDA Link 06/2012 - 05/2004
6	Histidine DecarboxylaseIBA 04/2011 - 01/2003
6	Matrix Metalloproteinases (MMPs)IBA 06/2010 - 10/2002
5	ParaffinIBA 08/2016 - 02/2013
4	Protein Isoforms (Isoforms)IBA 08/2016 - 07/2005
4	PeroxiredoxinsIBA 01/2016 - 10/2008
4	Apolipoproteins E (ApoE)IBA 02/2015 - 04/2011
4	Glucose (Dextrose)FDA LinkGeneric 06/2014 - 08/2010
3	CytokinesIBA 12/2018 - 01/2004
3	AntioxidantsIBA 01/2016 - 10/2008
3	MAP Kinase Kinase Kinase 5IBA 03/2014 - 07/2011
3	Streptozocin (Streptozotocin)FDA Link 12/2013 - 11/2010
3	Nitric Oxide Synthase (NO Synthase)IBA 01/2010 - 07/2005
2	CollagenIBA 01/2019 - 11/2012
2	Histamine H1 Receptors (Histamine H1 Receptor)IBA 12/2016 - 02/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 11/2012
2	Polypeptide N-acetylgalactosaminyltransferaseIBA 01/2016 - 12/2015
2	Biomarkers (Surrogate Marker)IBA 01/2016 - 05/2008
2	SurvivinIBA 02/2015 - 04/2011
2	Chemokine CCL22IBA 01/2015 - 10/2012
2	LipidsIBA 12/2013 - 09/2010
2	AntibodiesIBA 11/2011 - 01/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2010 - 06/2009
2	LDL CholesterolIBA 09/2010 - 01/2005
2	Histidine (L-Histidine)FDA Link 03/2010 - 06/2004
2	Matrix Metalloproteinase 12IBA 05/2008 - 04/2006
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 02/2008 - 02/2005
2	Superoxide DismutaseIBA 01/2008 - 07/2006
2	CarrageenanIBA 10/2004 - 06/2004
1	VimentinIBA 01/2018
1	N-AcetylgalactosaminyltransferasesIBA 08/2016
1	Peptides (Polypeptides)IBA 08/2016
1	UDP-N-acetylgalactosamine polypeptide N-acetylgalactosaminyltransferase 6IBA 08/2016
1	GlycosyltransferasesIBA 08/2016
1	Bile Acids and Salts (Bile Acids)IBA 07/2016
1	Choline (Choline Chloride)IBA 01/2016
1	Methionine (L-Methionine)FDA Link 01/2016
1	von Willebrand FactorIBA 05/2015
1	thiamine triphosphorate (TTP)IBA 05/2015
1	Histamine H2 ReceptorsIBA 02/2015
1	HMGB1 Protein (HMG1)IBA 10/2014
1	HMGB2 ProteinIBA 10/2014
1	Dextran SulfateIBA 01/2014
1	ZonarolIBA 01/2014
1	ProdrugsIBA 01/2014
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2014
1	hydroquinone (Esoterica)FDA Link 01/2014
1	Transaminases (Aminotransferases)IBA 12/2013
1	FructoseIBA 12/2013
1	AdiponectinIBA 12/2013
1	Adiponectin ReceptorsIBA 12/2013

Therapy/Procedure

5	Ligation 03/2014 - 12/2002
3	Therapeutics 10/2012 - 05/2003
1	Cell Transplantation 01/2019